Delayed response (DR) tasks represent the classic paradigm for studying working memory in both animals and humans. Working memory refers to the temporary storage of information in a “buffer” for rehearsal and organization of new information, and frontal systems are thought to subserve this process. Frontal working memory systems are also involved in the active retrieval of previously stored information through temporal tagging and organization of retrieval strategies. The hippocampus and other posterior brain regions, in contrast, are thought to be more involved in memory consolidation and permanent storage. Studies utilizing DR tasks have been used to elucidate the neuroanatomical organization of memory systems in the brain through behavioral, lesion, and electrophysiological studies.
In DR tasks, information is presented to a.